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| | Issue Date | Title | Contributor(s) | Type | Cat. |
| 1 | 2024 | Novel insights in phosphodiesterase 4 subtype inhibition to target neuroinflammation and stimulate remyelination | SCHEPERS, Melissa; VANMIERLO, Tim | Journal Contribution | A2 |
| 2 | 2024 | The sphingosine-1-phosphate receptor 1 modulator ponesimod repairs cuprizone-induced demyelination and induces oligodendrocyte differentiation | WILLEMS, Emily; SCHEPERS, Melissa; PICCART, Elisabeth; WOLFS, Esther; HELLINGS, Niels; Ait-Tihyaty, Maria; VANMIERLO, Tim | Journal Contribution | A1 |
| 3 | 2024 | Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays | VAN VEGGEL, Lieve; Mocking, Tamara A. M.; Sijben, Hubert J.; Liu, Rongfang; Gonzalez, Marina Gorostiola; Dilweg, Majlen A.; Royakkers, Jeroen; Li, Anna; Kumar, Vijay; Dong, Yin Yao; Bullock, Alex; Sauer, David B.; Dilien , Hanne; van Westen, Gerard J. P.; Schreiber, Rudy; Heitman, Laura H.; VANMIERLO, Tim | Journal Contribution | A1 |
| 4 | 2024 | The Impact of Sample Storage on Blood Methylation: Towards Assessing Myelin Gene Methylation as a Biomarker for Progressive Multiple Sclerosis | TIANE, Assia; SOMERS, Veerle; HELLINGS, Niels; van den Hove, DLA; VANMIERLO, Tim | Journal Contribution | A1 |
| 5 | 2023 | Unleashing Spinal Cord Repair: The Role of cAMP-Specific PDE Inhibition in Attenuating Neuroinflammation and Boosting Regeneration after Traumatic Spinal Cord Injury | Mussen, Femke; VAN BROECKHOVEN, Jana; HELLINGS, Niels; SCHEPERS, Melissa; VANMIERLO, Tim | Journal Contribution | A1 |
| 6 | 2023 | Phosphodiesterase (PDE) 4 inhibition boosts Schwann cell myelination in a 3D regeneration model | SCHEPERS, Melissa; Malheiro, Afonso; Gamardo, Adrian Seijas; HELLINGS, Niels; Prickaerts, Jos; Moroni, Lorenzo; VANMIERLO, Tim; Wieringa, Paul | Journal Contribution | A1 |
| 7 | 2023 | Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases | ZHAN, Na; Wang, Boyang; MARTENS, Nikita; Liu , Yankai; Zhao, Shangge; Voortman, Gardi; Van Rooij, Jeroen; Leijten, Frank; VANMIERLO, Tim; Kuipers, Folkert; Jonker, Johan W.; Bloks, Vincent W.; Luetjohann, Dieter; Palumbo, Marcella; Zimetti, Francesca; Adorni, Maria Pia; Liu, Hongbing; Mulder, Monique T. | Journal Contribution | A1 |
| 8 | 2023 | sGC modulators as cognitive enhancers: neuronal and/ or vascular? | Prickaerts, Jos; NELISSEN, Ellis; VANMIERLO, Tim; Sandner, Peter | Journal Contribution | M |
| 9 | 2023 | Brain-penetrant sGC stimulator BAY-747 and activator runcaciguat act as cognitive enhancers via differential neuroplastic mechanisms | NELISSEN, Ellis; VANMIERLO, Tim; Sandner, Peter; Prickaerts, Jos | Journal Contribution | M |
| 10 | 2023 | Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-beta pathology | PAES, Dean; SCHEPERS, Melissa; WILLEMS, Emily; ROMBAUT, Ben; TIANE, Assia; Solomina, Yevgeniya; Tibbo, Amy; Blair, Connor; Kyurkchieva, Elka; Baillie, George S.; Ricciarelli, Roberta; Brullo, Chiara; Fedele, Ernesto; Bruno, Olga; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, Jos | Journal Contribution | A1 |
| 11 | 2023 | From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions | TIANE, Assia; SCHEPERS, Melissa; Reijnders, Rick A.; VAN VEGGEL, Lieve; CHENINE, Sarah; ROMBAUT, Ben; Dempster, Emma; Verfaillie, Catherine; Wasner, Kobi; Gruenewald, Anne; Prickaerts, Jos; Pishva, Ehsan; HELLINGS, Niels; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A1 |
| 12 | 2023 | Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood-brain barrier impairment | Manukjan, Narek; Majcher, Daria; Leenders, Peter; Caiment, Florian; van Herwijnen, Marcel; Smeets, Hubert J. J.; Suidgeest, Ernst; van der Weerd, Louise; VANMIERLO, Tim; Jansen, Jacobus F. A.; Backes, Walter H. H.; van Oostenbrugge, Robert J. J.; Staals, Julie; Fulton, Daniel; Ahmed, Zubair; Blankesteijn, W. Matthijs; Foulquier, Sebastien | Journal Contribution | A1 |
| 13 | 2023 | Presynaptic Release-Regulating Sphingosine 1-Phosphate 1/3 Receptors in Cortical Glutamatergic Terminals: Adaptations in EAE Mice and Impact of Therapeutic FTY720 | Roggeri, Alessandra; Olivero, Guendalina; Usai, Cesare; VANMIERLO, Tim; Pittaluga, Anna | Journal Contribution | A1 |
| 14 | 2023 | Generation of a ST3GAL3 null mutant induced pluripotent stem cell (iPSC) line (UKWMPi002-A-3) by CRISPR/Cas9 genome editing | DIOUF, David; Vitale, Maria Rosaria; Zoeller, Johanna Eva Maria; Pineau, Ana -Magdalena; Klopocki, Eva; Hamann, Catharina; Ziegler, Georg Christoph; VANMIERLO, Tim; Van den Hove, Daniel; Lesch, Klaus-Peter | Journal Contribution | A1 |
| 15 | 2023 | Soluble guanylyl cyclase: A novel target for the treatment of vascular cognitive impairment? | NELISSEN, Ellis; SCHEPERS, Melissa; PONSAERTS, Laura; Foulquier, Sebastien; BRONCKAERS, Annelies; VANMIERLO, Tim; Sandner, Peter; Prickaerts, Jos | Journal Contribution | A1 |
| 16 | 2023 | A perspective on causality assessment in epigenetic research on neurodegenerative disorders | KOULOUSAKIS, Philippos; TIANE, Assia; HELLINGS, Niels; Prickaerts, Jos; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A2 |
| 17 | 2023 | Exogenous Oxytocin Administration Restores Memory in Female APP/PS1 Mice | KOULOUSAKIS, Philippos; WILLEMS, Emily; SCHEPERS, Melissa; ROMBAUT, Ben; Prickaerts, Jos; VANMIERLO, Tim; van den Hove, Daniel | Journal Contribution | A1 |
| 18 | 2023 | Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis | SCHEPERS, Melissa; PAES, Dean; TIANE, Assia; ROMBAUT, Ben; PICCART, Elisabeth; VAN VEGGEL, Lieve; GERVOIS, Pascal; Brullo, Chiara; Bruno, Olga; Fedele, Ernesto; Ricciarelli, Roberta; Ffrench-Constant, Charles; Bechler, Marie E.; Schaik, Pauline van; WOLFS, Esther; LAMBRICHTS, Ivo; Baron, Wia; LEFEVERE, Evy; Wasner, Kobi; Gruenewald, Anne; Verfaillie, Catherine; Wieringa, Paul; Prickaerts, Jos; BROUX, Bieke; BAETEN, Paulien; HELLINGS, Niels; VANMIERLO, Tim | Journal Contribution | A1 |
| 19 | 2023 | Cerebral microvascular endothelial cell-derived extracellular vesicles regulate blood - brain barrier function | HOSSEINKHANI, Baharak; DURAN, Gayel; HOEKS, Cindy; HERMANS, Doryssa; SCHEPERS, Melissa; BAETEN, Paulien; POELMANS, Joren; Coenen, Britt; Bekar, Kuebra; Pintelon, Isabel; Timmermans , Jean-Pierre; VANMIERLO, Tim; MICHIELS, Luc; HELLINGS, Niels; BROUX, Bieke | Journal Contribution | A1 |
| 20 | 2023 | Shortening arthrodesis combined with limited fasciectomy in severe recurrent Dupuytren's disease of the fifth finger | VANMIERLO, Bert; Van Eecke, Eduard; Decramer, Arne; VANMIERLO, Tim; Van Royen, Kjell; Goubau, Jean | Journal Contribution | A1 |
| 21 | 2023 | Therapeutic administration of mouse mast cell protease 6 improves functional recovery after traumatic spinal cord injury in mice by promoting remyelination and reducing glial scar formation | VANGANSEWINKEL, Tim; LEMMENS, Stefanie; TIANE, Assia; GEURTS, Nathalie; DOOLEY, Dearbhaile; VANMIERLO, Tim; Pejler, Gunnar; HENDRIX, Sven | Journal Contribution | A1 |
| 22 | 2023 | Activation of Liver X Receptors and Peroxisome Proliferator-Activated Receptors by Lipid Extracts of Brown Seaweeds: A Potential Application in Alzheimer's Disease? | MARTENS, Nikita; ZHAN, Na; Voortman, Gardi; Leijten, Frank P. J.; van Rheenen, Connor; van Leerdam, Suzanne; Geng, Xicheng; HUYBRECHTS, Michiel; Liu, Hongbing; Jonker, Johan W. W.; Kuipers, Folkert; Lutjohann, Dieter; VANMIERLO, Tim; Mulder, Monique T. T. | Journal Contribution | A1 |
| 23 | 2023 | Carnosine synthase deficiency aggravates neuroinflammation in multiple sclerosis | SPAAS, Jan; Van der Stede, Thibaux; de Jager, Sarah; VAN DE WATERWEG BERENDS, Annet; TIANE, Assia; Baelde, Hans; Baba, Shahid P.; Eckhardt, Matthias; WOLFS, Esther; VANMIERLO, Tim; HELLINGS, Niels; OP 'T EIJNDE, Bert; Derave, Wim | Journal Contribution | A1 |
| 24 | 2022 | Ponesimod, mono-selective sphingosine-1-phosphate receptor 1 modulator enhances oligodendrocyte precursor cell differentiation | WILLEMS, Emily; SCHEPERS, Melissa; Ait-Tihyaty, M.; VANMIERLO, Tim | Journal Contribution | M |
| 25 | 2022 | The monoselective sphingosine-1-phosphate receptor-1 modulator ponesimod enhances remyelination in the cuprizone model of demyelination | SCHEPERS, Melissa; WILLEMS, Emily; Ait-Tihyaty, M.; VANMIERLO, Tim | Journal Contribution | M |
| 26 | 2022 | BROWN SEAWEEDS ACTIVATING LIVER X RECEPTORS: POTENTIAL ROLE IN THE PREVENTION OF NEURODEGENERATIVE AND CARDIOMETABOLIC DISEASES | Mulder, M. T.; MARTENS, Nikita; Zhan , N.; Voortman-Minderman, G.; Liu, H.; Kuipers, F.; Jonker, H.; Luetjohann, D.; VANMIERLO, Tim | Journal Contribution | M |
| 27 | 2022 | LXR-beta signalling is a key mediator in the pathogenesis of aortic valve stenosis and its prevention by saringosterol | Noethel, M.; Schmidt, A.; Mulder, M. T.; VANMIERLO, Tim; Friedrichs, S.; Schmidt , S. V.; Voortman, G.; Goody, P.; Zimmer, S.; Nickenig, G.; Luetjohann, D.; Jehle, J. | Journal Contribution | M |
| 28 | 2022 | Computational investigation of the dynamic control of cAMP signaling by PDE4 isoform types | PAES, Dean; Hermans, Sammy; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, Jos; Carlier, Aurelie | Journal Contribution | A1 |
| 29 | 2022 | The sGC stimulator BAY-747 and activator runcaciguat can enhance memory in vivo via differential hippocampal plasticity mechanisms | NELISSEN, Ellis; Possemis, Nina; Van Goethem, Nick P.; SCHEPERS, Melissa; Mulder-Jongen, Danielle A. J.; Dietz, Lisa; JANSSEN, Wiebke; Gerisch, Michael; Huser, Jorg; Sandner, Peter; VANMIERLO, Tim; Prickaerts, Jos | Journal Contribution | A1 |
| 30 | 2022 | THE USE OF SEAWEED-DERIVED PHYTOSTEROLS TO DEFEAT ALZHEIMER'S DISEASE | MARTENS, Nikita; SCHEPERS, Melissa; ZHAN, Na; Leijten, F.; Voortman-Minderman, G.; TIANE, Assia; ROMBAUT, Ben; Poisquet, Janne; Van de Sande, N.; Kerksiek, A.; Kuipers, F.; Jonker, J. W.; Liu, H.; Luetjohann, D.; VANMIERLO, Tim; Mulder, M. T. | Journal Contribution | M |
| 31 | 2022 | Editorial: Cyclic Nucleotide Phosphodiesterases (PDEs) in Immune Regulation and Inflammation | Brocke, Stefan; Epstein, Paul M.; Nelson, Robert; VANMIERLO, Tim | Journal Contribution | A2 |
| 32 | 2022 | The Selective Sphingosine-1-Phosphate Receptor 1 (S1P1) Modulator Ponesimod Enhances Murine Oligodendrocyte Precursor Cell (OPC) Differentiation and Retains OPC Migration | Ait-Tihyaty, M.; PICCART, Elisabeth; SCHEPERS, Melissa; WILLEMS, E; DiBernardo, A.; VANMIERLO, Tim | Journal Contribution | M |
| 33 | 2022 | INCREASING CAMP LEVELS BY INHIBITING PHOSPHODIESTERASE 4D IMPROVES NERVE CONDUCTION AND FUNCTIONAL RECOVERY IN A MOUSE MODEL FOR CHARCOT MARIE TOOT 1A | VANGANSEWINKEL, Tim; SCHEPERS, Melissa; LIBBERECHT, Karen; Jacobs , Darren; PICCART, Elisabeth; JEURISSEN, Hanne; Prior, Robert; Ricciarelli, Roberta; Bruno, Olga; Fedele, Ernesto; Brullo, Chiara; Prickaerts, Jos; Van Den Bosch , Ludo; VANMIERLO, Tim; LAMBRICHTS, Ivo; WOLFS, Esther | Journal Contribution | M |
| 34 | 2021 | DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation. | TIANE, Assia; SCHEPERS, Melissa; Riemens, R.; ROMBAUT, Ben; VANDORMAEL, Patrick; SOMERS, Veerle; Prickaerts, J.; HELLINGS, Niels; Van den Hove, D.; VANMIERLO, Tim | Journal Contribution | M |
| 35 | 2021 | Disrupted-In-Schizophrenia 1 controls microglial movement and phagocytosis | KESSELS, Sofie; BERDEN, Lisa; AGUIAR ALPIZAR, Yeranddy; BEEKEN, Jolien; TRIPPAERS, Chloe; ROMBAUT, Ben; Ishizuka, K; Nguyen, L; Antel, J; Healy, L; Cowley, S; DEWACHTER, Ilse; Rigo, J; VANMIERLO, Tim; Sawa, A; BRONE, Bert | Journal Contribution | M |
| 36 | 2021 | P.0261 Investigation of cdh13’s role in neurodevelopmental disorders using isogenic induced pluripotent stem cell (ipsc) lines and different cdh13 snp variants | Vitale, M. R.; Zoeller, J. E. M.; Ziegler, G. C.; Von den Hove, D.; VANMIERLO, Tim; Lesch, K. P. | Journal Contribution | M |
| 37 | 2021 | Neuroinflammation in Ischemic Stroke: Inhibition of cAMP-Specific Phosphodiesterases (PDEs) to the Rescue | PONSAERTS, Laura; ALDERS, Lotte; SCHEPERS, Melissa; de Oliveira, RMW; Prickaerts, J; VANMIERLO, Tim; BRONCKAERS, Annelies | Journal Contribution | A1 |
| 38 | 2021 | 24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer’s Disease | MARTENS, Nikita; SCHEPERS, Melissa; Zhan, Na; Leijten, Frank; Voortman, Gardi; TIANE, Assia; ROMBAUT, Ben; POISQUET, Janne; van de Sande, Nienke; Kerksiek, Anja; Kuipers, Folkert; Jonker, Johan W.; Liu, Hongbing; Lütjohann, Dieter; VANMIERLO, Tim; Mulder, Monique T. | Journal Contribution | A1 |
| 39 | 2021 | Positive effects of roflumilast on behavior, neuroinflammation, and white matter injury in mice with global cerebral ischemia | Vilhena, Emanuella R.; Bonato, Jessica M.; SCHEPERS, Melissa; Kunieda, Juliana K. C.; Milani, Humberto; VANMIERLO, Tim; Prickaerts, Jos; de Oliveira, Rubia M. W. | Journal Contribution | A1 |
| 40 | 2021 | Dietary advanced glycation endproducts (AGEs) increase their concentration in plasma and tissues, result in inflammation and modulate gut microbial composition in mice; evidence for reversibility | van Dongen, Katja C. W.; Linkens, Armand M. A.; WETZELS, Suzan; WOUTERS, Kristiaan; VANMIERLO, Tim; van de Waarenburg, Marjo P. H.; Scheijen, Jean L. J. M.; de Vos, Willem M.; Belzer, Clara; Schalkwijk, Casper G. | Journal Contribution | A1 |
| 41 | 2021 | The Molecular Biology of Phosphodiesterase 4 Enzymes as Pharmacological Targets: An Interplay of Isoforms, Conformational States, and Inhibitors | PAES, Dean; SCHEPERS, Melissa; ROMBAUT, Ben; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, Jos; Michel, Martin | Journal Contribution | A1 |
| 42 | 2021 | DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation | TIANE, Assia; SCHEPERS, Melissa; Riemens, Renzo; ROMBAUT, Ben; VANDORMAEL, Patrick; SOMERS, Veerle; Prickaerts, Jos; HELLINGS, Niels; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A1 |
| 43 | 2021 | Liver X receptor beta deficiency attenuates autoimmune-associated neuroinflammation in a T cell-dependent manner | BOGIE, Jeroen; VANMIERLO, Tim; VANMOL, Jasmine; TIMMERMANS, Silke; MAILLEUX, Jo; Wijnands, Erwin; NELISSEN, Katherine; Gustafsson, Jan-Ake; STINISSEN, Piet; WOUTERS, Kristiaan; Steffensen, Knut R.; Mulder, Monique; Zelcer, Noam; HENDRIKS, Jerome | Journal Contribution | A1 |
| 44 | 2021 | Brown Seaweed Food Supplementation: Effects on Allergy and Inflammation and Its Consequences | Olsthoorn, Simone E. M.; Tillema, Berend; VANMIERLO, Tim; Kraan, Stefan; Leenen, Pieter J. M.; Mulder, Monique T.; Wang, Xi | Journal Contribution | A1 |
| 45 | 2021 | PDE inhibition in distinct cell types to reclaim the balance of synaptic plasticity | ROMBAUT, Ben; KESSELS, Sofie; SCHEPERS, Melissa; TIANE, Assia; PAES, Dean; Solomina, Yevgeniya; PICCART, Elisabeth; van den Hove, Daniel; BRONE, Bert; Prickaerts, Jos; VANMIERLO, Tim | Journal Contribution | A1 |
| 46 | 2021 | Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders | SPAAS, Jan; VAN VEGGEL, Lieve; SCHEPERS, Melissa; TIANE, Assia; VAN HORSSEN, Jack; WILSON, David; Moya, Pablo R.; PICCART, Elisabeth; HELLINGS, Niels; OP 'T EIJNDE, Bert; Derave, Wim; Schreiber, Rudy; VANMIERLO, Tim | Journal Contribution | A1 |
| 47 | 2021 | 24(R, S)-Saringosterol - From artefact to a biological medical agent | VANBRABANT, Kenneth; Van Meel, David; Kerksiek, Anja; Friedrichs, Silvia; Dubbeldam, Marco; SCHEPERS, Melissa; Zhan, Na; Gutbrod, Katharina; Dörmann, Peter; Liu, Hong-Bing; Mulder, Monique T; VANMIERLO, Tim; Lütjohann, Dieter | Journal Contribution | A1 |
| 48 | 2021 | Corrigendum: Edible seaweed-derived constituents: an undisclosed source of neuroprotective compounds | SCHEPERS, Melissa; MARTENS, Nikita; TIANE, Assia; VANBRABANT, Kenneth; Liu, Hong-Bing; Lütjohann, Dieter; Mulder, Monique; VANMIERLO, Tim | Journal Contribution | M |
| 49 | 2021 | Increased isoform-specific phosphodiesterase 4D expression is associated with pathology and cognitive impairment in Alzheimer’s disease | PAES, Dean; Lardenoije, Roy; CAROLLO, Riccardo; Roubroeks, Janou A. Y.; SCHEPERS, Melissa; Coleman, Paul; Mastroeni, Diego; Delvaux, Elaine; Pishva, Ehsan; Lunnon, Katie; VANMIERLO, Tim; van den Hove, Daniel; Prickaerts, Jos | Journal Contribution | A1 |
| 50 | 2021 | Generation of induced pluripotent stem cell (iPSC) lines carrying a heterozygous (UKWMPi002-A-1) and null mutant knockout (UKWMPi002-A-2) of Cadherin 13 associated with neurodevelopmental disorders using CRISPR/Cas9 | Vitale, Maria Rosaria; Zoeller, Johanna Eva Maria; Jansch, Charline; Janz, Anna; Edenhofer, Frank; Klopocki, Eva; van den Hove, Daniel; VANMIERLO, Tim; Rivero, Olga; Kasri, Nael Nadif; Ziegler, Georg Christoph; Lesch, Klaus-Peter | Journal Contribution | A1 |
| 51 | 2021 | CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia | LODDER, Chritica; Scheyltjens, I; STANCU, Ilie Cosmin; BOTELLA LUCENA, Pablo; GUTIERREZ DE RAVE, Manu; VANHERLE, Sarah; VANMIERLO, Tim; CREMERS, Niels; VANRUSSELT, Hannah; BRONE, Bert; Hanseeuw, B; Octave, JN; Bottelbergs, A; Movahedi, K; DEWACHTER, Ilse | Journal Contribution | A1 |
| 52 | 2021 | Carnosine quenches the reactive carbonyl acrolein in the central nervous system and attenuates autoimmune neuroinflammation | SPAAS, Jan; FRANSSEN, Wouter; KEYTSMAN, Charly; Blancquaert, Laura; VANMIERLO, Tim; BOGIE, Jeroen; BROUX, Bieke; HELLINGS, Niels; VAN HORSSEN, Jack; Posa, Dheeraj Kumar; Hoetker, David; Baba, Shahid P.; Derave, Wim; OP 'T EIJNDE, Bert | Journal Contribution | A1 |
| 53 | 2020 | Editorial: Neuro-Immune Connections to Enable Repair in CNS Disorders | VANMIERLO, Tim; VAN HORSSEN, Jack; HELLINGS, Niels; BROUX, Bieke | Journal Contribution | A1 |
| 54 | 2020 | Sphingosine-1-Phosphate Receptor Modulators and Oligodendroglial Cells: Beyond Immunomodulation | Roggeri, Alessandra; SCHEPERS, Melissa; TIANE, Assia; ROMBAUT, Ben; VAN VEGGEL, Lieve; HELLINGS, Niels; Prickaerts, Jos; Pittaluga, Anna; VANMIERLO, Tim | Journal Contribution | A1 |
| 55 | 2020 | Edible seaweed-derived constituents: an undisclosed source of neuroprotective compounds | SCHEPERS, Melissa; MARTENS, Nikita; TIANE, Assia; VANBRABANT, Kenneth; Liu, Hong-Bing; Lütjohann, Dieter; Mulder, Monique; VANMIERLO, Tim | Journal Contribution | A1 |
| 56 | 2020 | Oncostatin m-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination | HOUBEN, Evelien; JANSSENS, Kris; HERMANS, Doryssa; Vandooren, J.; Van den Haute, C.; SCHEPERS, Melissa; VANMIERLO, Tim; LAMBRICHTS, Ivo; Baekelandt, V.; VAN HORSSEN, Jack; Baron, W.; OPDENAKKER, Ghislain; BROUX, Bieke; SLAETS, Leen; HELLINGS, Niels | Journal Contribution | M |
| 57 | 2020 | Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination | HOUBEN, Evelien; JANSSENS, Kris; HERMANS, Doryssa; Vandooren, Jennifer; Van den Haute, Chris; SCHEPERS, Melissa; VANMIERLO, Tim; LAMBRICHTS, Ivo; VAN HORSSEN, Jack; Baekelandt, Veerle; OPDENAKKER, Ghislain; Baron, Wia; BROUX, Bieke; Slaets, Helena; HELLINGS, Niels | Journal Contribution | A1 |
| 58 | 2019 | DIETARY SARGASSUM FUSIFORME IMPROVES MEMORY AND REDUCES AMYLOID PLAQUE LOAD IN AN ALZHEIMER'S DISEASE MOUSE MODEL | Mulder, M.; BOGIE, Jeroen; HOEKS, Cindy; SCHEPERS, Melissa; Tuabe, A.; Leijten, F.; Chintapakorn, Y.; Struik, D.; Liu, H. B.; HELLINGS, Niels; Martinez-Martinez, P.; Jonker, J.; DEWACHTER, Ilse; Walter, J.; HENDRIKS, Jerome; Groen, A.; Staels, B.; Lutjohann, D.; VANMIERLO, Tim | Journal Contribution | M |
| 59 | 2019 | Dietary carnosine intake improves outcomes in Experimental Autoimmune Encephalomyelitis | SPAAS, Jan; FRANSSEN, Wouter; VANMIERLO, Tim; BOGIE, Jeroen; Derave, W.; OP 'T EIJNDE, Bert | Journal Contribution | M |
| 60 | 2019 | Relieving the epigenetic blockade in progressive multiple sclerosis - making remyelination accessible again | TIANE, Assia; SCHEPERS, Melissa; PAES, Dean; Prickaerts, J.; van den Hove, D.; HELLINGS, Niels; VANMIERLO, Tim | Journal Contribution | M |
| 61 | 2019 | Sargassum fusiforme improves memory and reduces amyloid plaque pathology in an Alzheimer's disease mouse model | BOGIE, Jeroen; HOEKS, Cindy; SCHEPERS, Melissa; TIANE, Assia; CUYPERS, Ann; Leijten, F.; Chintapakorn, Y.; Suttyut, T.; Pornpakakul, S.; Struik, D.; Kerksiek, A.; Liu, H.; HELLINGS, Niels; Martinez-Marinez, P.; Jonker, J.; DEWACHTER, Ilse; Sijbrands, E.; Walter, J.; HENDRIKS, Jerome; Groen, A.; Staels, B.; Luetjohann, D.; Mulder, M.; VANMIERLO, Tim | Journal Contribution | M |
| 62 | 2019 | Phosphodiesterase 4D inhibition boosts remyelination in multiple sclerosis | SCHEPERS, Melissa; PAES, Dean; TIANE, Assia; HOUBEN, Els; Bruno, O.; Brullo, C.; HELLINGS, Niels; Prickaerts, J.; VANMIERLO, Tim | Journal Contribution | M |
| 63 | 2019 | Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model | BOGIE, Jeroen; HOEKS, Cindy; SCHEPERS, Melissa; TIANE, Assia; CUYPERS, Ann; Leijten, Frank; Chintapakorn, Yupyn; Suttiyut, Thiti; Pornpakakul, Surachai; Struik, Dicky; Kerksiek, Anja; Liu, Hong-Bing; HELLINGS, Niels; Martinez-Martinez, Pilar; Jonker, Johan W.; DEWACHTER, Ilse; Sijbrands, Eric; Walter, Jochen; HENDRIKS, Jerome; Groen, Albert; Staels, Bart; Lutjohann, Dieter; VANMIERLO, Tim; Mulder, Monique | Journal Contribution | A1 |
| 64 | 2019 | ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury | SOMMER, Daniela; Corstjens, Inge; SANCHEZ, Selien; DOOLEY, Dearbhaile; LEMMENS, Stefanie; VAN BROECKHOVEN, Jana; BOGIE, Jeroen; VANMIERLO, Tim; Vidal, Pia M.; Rose-John, Stefan; GOU FABREGAS, Myriam; HENDRIX, Sven | Journal Contribution | A1 |
| 65 | 2019 | Plant-based sterols and stanols in health & disease: "Consequences of human development in a plant-based environment?" | Plat, J.; Baumgartner, S.; VANMIERLO, Tim; Luetjohann, D.; Calkins, K. L.; Burrin, D. G.; Guthrie, G.; Thijs, C.; Te Velde, A. A.; Vreugdenhil, A. C. E.; Sverdlov, R.; Garssen, J.; WOUTERS, Kristiaan; Trautwein, E. A.; Wolfs, T. G.; van Gorp, C.; Mulder, M. T.; Riksen, N. P.; Groen, A. K.; Mensink, R. P. | Journal Contribution | A1 |
| 66 | 2019 | Methylglyoxal-Derived Advanced Glycation Endproducts Accumulate in Multiple Sclerosis Lesions | WETZELS, Suzan; VANMIERLO, Tim; Scheijen, Jean L. J. M.; VAN HORSSEN, Jack; Amor, Sandra; SOMERS, Veerle; Schalkwijk, Casper G.; HENDRIKS, Jerome; WOUTERS, Kristiaan | Journal Contribution | A1 |
| 67 | 2019 | From OPC to Oligodendrocyte: An Epigenetic Journey | TIANE, Assia; SCHEPERS, Melissa; ROMBAUT, Ben; Hupperts, R; Prickaerts, J; HELLINGS, Niels; van den Hove, D; VANMIERLO, Tim | Journal Contribution | A1 |
| 68 | 2019 | Phosphodiesterase Type 4 Inhibition in CNS Diseases | Blokland, A; Heckman, P; VANMIERLO, Tim; Schreiber, R; PAES, Dean; Prickaerts, J | Journal Contribution | A1 |
| 69 | 2019 | The role of receptor MAS in microglia-driven retinal vascular development | Foulquier, S.; Caolo, V.; Swennen, G.; Milanova, I.; Reinhold, S.; Recarti, C.; Alenina, N.; Bader, M.; Steckelings, U. M.; VANMIERLO, Tim; Post, M. J.; Jones, E. A.; van Oostenbrugge, R. J.; Unger, T. | Journal Contribution | A1 |
| 70 | 2019 | Liver X Receptor Alpha Is Important in Maintaining Blood-Brain Barrier Function | WOUTERS, Elien; de Wit, Nienke M.; VANMOL, Jasmine; van der Pol, Susanne M. A.; Hof, Bert van Het; SOMMER, Daniela; LOIX, Melanie; Geerts, Dirk; Gustafsson, Jan Ake; Steffensen, Knut R.; VANMIERLO, Tim; BOGIE, Jeroen; HENDRIKS, Jerome; de Vries, Helga E. | Journal Contribution | A1 |
| 71 | 2019 | Targeting Phosphodiesterases-Towards a Tailor-Made Approach in Multiple Sclerosis Treatment | SCHEPERS, Melissa; TIANE, Assia; PAES, Dean; SANCHEZ, Selien; ROMBAUT, Ben; PICCART, Elisabeth; Rutten, Bart P. F.; BRONE, Bert; HELLINGS, Niels; Prickaerts, Jos; VANMIERLO, Tim | Journal Contribution | A1 |
| 72 | 2018 | Oncostatin M-induced astrocytic TIMP-1 enables remyelination | HOUBEN, Evelien; JANSSENS, Kim; LAMBRICHTS, Ivo; Baekelandt, V.; SCHEPERS, Melissa; VANMIERLO, Tim; SLAETS, Leen; BROUX, Bieke; HELLINGS, Niels | Journal Contribution | M |
| 73 | 2018 | Roflumilast promotes memory recovery and attenuates white matter injury in aged rats subjected to chronic cerebral hypoperfusion | Santiago, Amanda; Soares, Ligia Mendes; SCHEPERS, Melissa; Milani, Humberto; VANMIERLO, Tim; Prickaerts, Jos; Weffort de Oliveira, Rubia M. | Journal Contribution | A1 |
| 74 | 2018 | Gestational stress in mouse dams negatively affects gestation and postpartum hippocampal BDNF and P11 protein levels | VANMIERLO, Tim; DE VRY, Jochen; NELISSEN, Ellis; Sierksma, Annerieke; Roumans, Nadia; STEINBUSCH, Harry; Wennogle, Lawrence P.; van den Hove, Daniel; Prickaerts, Jos | Journal Contribution | A1 |
| 75 | 2018 | Progress and perspectives in plant sterol and plant stanol research | Jones, Peter J. H.; Shamloo, Maryam; MacKay, Dylan S.; Rideout, Todd C.; Myrie, Semone B.; Plat, Jogchum; Roullet, Jean-Baptiste; Baer, David J.; Calkins, Kara L.; Davis, Harry R.; Duell, P. Barton; Ginsberg, Henry; Gylling, Helena; Jenkins, David; Luetjohann, Dieter; Moghadasian, Mohammad; Moreau, Robert A.; Mymin, David; Ostlund, Richard E., Jr.; Ras, Rouyanne T.; Reparaz, Javier Ochoa; Trautwein, Elke A.; Turley, Stephen; VANMIERLO, Tim; Weingaetner, Oliver | Journal Contribution | A1 |
| 76 | 2018 | Active liver X receptor signaling in phagocytes in multiple sclerosis lesions | MAILLEUX, Jo; VANMIERLO, Tim; BOGIE, Jeroen; WOUTERS, Elien; Lütjohann, Dieter; HENDRIKS, Jerome; VAN HORSSEN, Jack | Journal Contribution | A1 |
| 77 | 2018 | Advanced Glycation Endproducts Are Increased in the Animal Model of Multiple Sclerosis but Cannot Be Reduced by Pyridoxamine Treatment or Glyoxalase 1 Overexpression | WETZELS, Suzan; WOUTERS, Kristiaan; Miyata, Toshio; Scheijen, Jean L. J. M.; HENDRIKS, Jerome; Schalkwijk, Casper G.; VANMIERLO, Tim | Journal Contribution | A1 |
| 78 | 2018 | Twelve Weeks of Medium-Intensity Exercise Therapy Affects the Lipoprotein Profile of Multiple Sclerosis Patients. | JORISSEN, Winde; VANMIERLO, Tim; WENS, Inez; SOMERS, Veerle; VAN WIJMEERSCH, Bart; BOGIE, Jeroen; Remaley, Alan; OP 'T EIJNDE, Bert; HENDRIKS, Jerome | Journal Contribution | A1 |
| 79 | 2018 | Limited daily feeding and intermittent feeding have different effects on regional brain energy homeostasis during aging | Smiljanic, Kosara; Todorovic, Smilja; Mladenovic Djordjevic, Aleksandra; VANMIERLO, Tim; Luetjohann, Dieter; Ivkovic, Sanja; Kanazir, Selma | Journal Contribution | A1 |
| 80 | 2018 | Targeting demyelination via α-secretases promoting sAPPα release to enhance remyelination in central nervous system | Llufriu-Dabén, Gemma; Carrete, Alex; Chierto, Elena; MAILLEUX, Jo; Camand, Emeline; Simon, Anne; VANMIERLO, Tim; Rose, Christiane; Allinquant, Bernadette; HENDRIKS, Jerome; Massaad, Charbel; Meffre, Delphine; Jafarian-Tehrania, Mehrnaz | Journal Contribution | A1 |
| 81 | 2017 | The phosphodiesterase 4 (PDE4) inhibitor roflumilast improves remyelination in a mouse model for multiple sclerosis | SCHEPERS, Melissa; MAILLEUX, Jo; BOGIE, Jeroen; van Goethem, N.; HELLINGS, Niels; HENDRIKS, Jerome; Prickaerts, J.; VANMIERLO, Tim | Journal Contribution | M |
| 82 | 2017 | Scavenger receptor collectin placenta 1 is a novel receptor 1 involved in the uptake of myelin by phagocytes | BOGIE, Jeroen; MAILLEUX, Jo; WOUTERS, Elien; JORISSEN, Winde; GRAJCHEN, Elien; VANMOL, Jasmine; WOUTERS, Kristiaan; HELLINGS, Niels; Van Horsen, Jack; VANMIERLO, Tim; HENDRIKS, Jerome | Journal Contribution | A1 |
| 83 | 2017 | Plant sterol ester diet supplementation increases serum plant sterols and markers of cholesterol synthesis, but has no effect on total cholesterol levels | Weingaertner, Oliver; Bogeski, Ivan; Kummerow, Carsten; Schirmer, Stephan H.; Husche, Constanze; VANMIERLO, Tim; Wagenpfeil, Gudrun; Hoth, Markus; Boehm, Michael; Luetjohann, Dieter; Laufs, Ulrich | Journal Contribution | A1 |
| 84 | 2017 | Early-postnatal iron deficiency impacts plasticity in the dorsal and ventral hippocampus in piglets | NELISSEN, Ellis; DE VRY, Jochen; Antonides, Alexandra; PAES, Dean; SCHEPERS, Melissa; van der Staay, Franz Josef; Prickaerts, Jos; VANMIERLO, Tim | Journal Contribution | A1 |
| 85 | 2017 | Relapsing-remitting multiple sclerosis patients display an altered lipoprotein profile with dysfunctional HDL | JORISSEN, Winde; WOUTERS, Elien; BOGIE, Jeroen; VANMIERLO, Tim; NOBEN, Jean-Paul; Sviridov, Denis; HELLINGS, Niels; SOMERS, Veerle; VALCKE, Roland; Vanwijmeersch, Bart; STINISSEN, Piet; Mulder, Monique T.; Remaley, Alan T.; HENDRIKS, Jerome | Journal Contribution | A1 |
| 86 | 2017 | Methylglyoxal-derived advanced glycation endproducts in multiple sclerosis | WETZELS, Suzan; WOUTERS, Kristiaan; Schalkwijk, Casper G.; VANMIERLO, Tim; HENDRIKS, Jerome | Journal Contribution | A1 |
| 87 | 2017 | Low-density lipoprotein receptor deficiency attenuates neuroinflammation through the induction of apolipoprotein | MAILLEUX, Jo; TIMMERMANS, Silke; NELISSEN, Katherine; VANMOL, Jasmine; VANMIERLO, Tim; VAN HORSSEN, Jack; BOGIE, Jeroen; HENDRIKS, Jerome | Journal Contribution | A1 |
| 88 | 2016 | The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses | VANMIERLO, Tim; Creemers, Pim; Akkerman, Sven; van Duinen, Marlies; Sambeth, Anke; DE VRY, Jochen; Uz, Tolga; Blokland, Arjan; Prickaerts, Jos | Journal Contribution | A1 |
| 89 | 2015 | Differential susceptibility to chronic social defeat stress relates to the number of Dnmt3a-immunoreactive neurons in the hippocampal dentate gyrus | Hammels, Caroline; Prickaerts, Jos; Kenis, Gunter; VANMIERLO, Tim; Fischer, Maximilian; STEINBUSCH, Harry; van Os, Jim; van den Hove, Daniel L. A.; Rutten, Bart P. F. | Journal Contribution | A1 |
| 90 | 2015 | Plant sterols: Friend or foe in CNS disorders? | VANMIERLO, Tim; BOGIE, Jeroen; MAILLEUX, Jo; VANMOL, Jasmine; Luetjohann, Dieter; Mulder, Monique; HENDRIKS, Jerome | Journal Contribution | A1 |
| 91 | 2014 | Cholesterol metabolism changes under long-term dietary restrictions while the cholesterol homeostasis remains unaffected in the cortex and hippocampus of aging rats | Smiljanic, Kosara; VANMIERLO, Tim; Djordjevic, Aleksandra Mladenovic; Perovic, Milka; Ivkovic, Sanja; Luetjohann, Dieter; Kanazir, Selma | Journal Contribution | A1 |
| 92 | 2014 | Long-term effects of prenatal allopurinol treatment on brain plasticity markers in low and normal birth weight piglets. | VANMIERLO, Tim; Prickaerts, Jos; Gieling, Elise T.; Bruder, Ann K.; van der Staay, Franz J. | Journal Contribution | A1 |
| 93 | 2014 | High fat diet exacerbates neuroinflammation in an animal model of multiple sclerosis by activation of the Renin Angiotensin system. | TIMMERMANS, Silke; BOGIE, Jeroen; VANMIERLO, Tim; Lütjohann, Dieter; STINISSEN, Piet; HELLINGS, Niels; HENDRIKS, Jerome | Journal Contribution | A1 |
| 94 | 2014 | PDE5 Inhibition Improves Object Memory in Standard Housed Rats but Not in Rats Housed in an Enriched Environment: Implications for Memory Models? | Akkerman, Sven; Prickaerts, Jos; Bruder, Ann K.; Wolfs, Kevin H. M.; DE VRY, Jochen; VANMIERLO, Tim; Blokland, Arjan | Journal Contribution | A1 |
| 95 | 2013 | Myelin alters the inflammatory phenotype of macrophages by activating PPARs | BOGIE, Jeroen; JORISSEN, Winde; MAILLEUX, Jo; Nijland, G. Philip; Zelcer, Noam; VANMIERLO, Tim; VAN HORSSEN, Jack; STINISSEN, Piet; HELLINGS, Niels; HENDRIKS, Jerome | Journal Contribution | A1 |
| 96 | 2013 | Aging Induces Tissue-Specific Changes in Cholesterol Metabolism in Rat Brain and Liver | Smiljanic, Kosara; VANMIERLO, Tim; Mladenovic Djordjevic, Aleksandra; Perovic, Milka; Loncarevic-Vasiljkovic, Natasa; Tesic, Vesna; Rakic, Ljubisav; Ruzdijic, Sabera; Lütjohann, Dieter; Kanazir, Selma | Journal Contribution | A1 |
| 97 | 2013 | 7,8-Dihydroxyflavone improves memory consolidation processes in rats and mice. | BOLLEN, Eva; VANMIERLO, Tim; Akkerman, Sven; Wouters, C.; STEINBUSCH, Harry; Prickaerts, Jos | Journal Contribution | A1 |
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